منابع مشابه
ADENOSINE IN THE CENTRAL NERVOUS SYSTEM
Besides being a metabolite of nucleotides like ATP, adenosine is a mediator of neuronal function in the central nervous system. Its actions are mediated by at least three extracellular receptors. In this review different aspects of adenosine such as biosynthesis, release, inactivation and its receptors are discussed. It also covers pre- and postsynaptic effects as well as postreceptor mecha...
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متن کاملRegeneration in the central nervous system.
Unlike neonatal axons, mammalian adult axons of the CNS do not regenerate after injury. This developmental loss of regenerative capacity, is correlated with the onset of myelination. Likewise, myelin, or myelin-associated components such as Nogo-A and myelin-associated glycoprotein (MAG) inhibit regeneration from older but not younger neurons. Identification of the molecular events responsible ...
متن کاملRegeneration of the adult central nervous system
Cloned mammals have bred naturally for the first time, researchers reported last month, but faced the most trying of times. Two endangered African wildcat clones have each given birth to a litter, a total of eight kittens in all. The first five kittens were born on July 26 to Madge, a clone of the wildcat Nancy. The second litter, consisting of three kittens, was born on August 2 to Caty, also ...
متن کاملCurrent concepts in central nervous system regeneration.
A dictum long-held has stated that the adult mammalian brain and spinal cord are not capable of regeneration after injury. Recent discoveries have, however, challenged this dogma. In particular, a more complete understanding of developmental neurobiology has provided an insight into possible ways in which neuronal regeneration in the central nervous system may be encouraged. Knowledge of the ro...
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ژورنال
عنوان ژورنال: Experimental Gerontology
سال: 2003
ISSN: 0531-5565
DOI: 10.1016/s0531-5565(02)00165-1